Nicolas Franco work has been exhibited at Tate Modern, London; Migros Museum für Gegenwartskunst, Zurich; MEIAC -Museo Extremeño e Iberoamericano de Arte Contemporáneo, Badajoz; Museo de Arte Contemporáneo de Santiago (MAC); Museo de Arte Contemporáneo de Lima; Museo Nacional de Bellas Artes de Santiago; Fundación CorpArtes, Santiago; MUUA, Antioquia; The Centre of Contemporary Art Znaki Czasu, Torun; Sala Alcalá 31, Madrid; La Conservera, Murcia;  among others.
He participated in the First Chilean Triennial and has received grants from institutions including the Mondrian Foundation, Fundacion Ama, Tecnopol UAH and Oxford University. His work is held in public and private collections including Tate Modern, Museo de la Memoria y los Derechos Humanos, Museo de Arte Contemporáneo de Santiago, Fundación AMA, Fundación Engel, Fundación Larivière, and Il Posto among others and has been reviewed in Artforum, The Financial Times, Wallpaper, ArtNexus and The Guardian. He has participated in several international art residencies such as De Ateliers and Gasworks.